Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas

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Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas.

Ependymomas are glial neoplasms occurring in any location throughout the central nervous system and supposedly are derived from radial glia cells. Recent data suggest that these tumors may have different biological and clinical behaviors according to their location. Pediatric supratentorial and infratentorial ependymoma (SE and IE) were compared with respect to clinical and radiological paramet...

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Childhood Intracranial Ependymoma Presenting as Cystic Supratentorial Brain Tumour

Approximately 50% of all childhood brain tumours arise in the infratentorial fossa and the most common tumours in this region of the brain are cerebellar astrocytomas, medulloblastomas, ependymomas, and brainstem gliomas [1]. Conversely in the suratentorial fossa, up to 20% of childhood tumours arise in the suprasellar region with craniopharyngiomas, visual pathway gliomas, and germinomas as th...

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cortical epandimoma with extention to thalamus

ependymomas are glial tumors originate from ependymal cells lining the ventricles and the central canal of the spinal cord. two thirds of ependymomas arise in the infratentorial or intraventriclesandone-third aredetected in supratentorial area. however supratentorial “cortical” ependymomas are veryuncommon. ependymomas are usually infratentorial, intraventricular tumor, including 2–9% of all ce...

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The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas.

PURPOSE Ependymomas are glial tumors of presumably radial glial origin that share morphologic similarities with ependymal cells. The molecular genetics of ependymomas of supratentorial, infratentorial, and spinal location is heterogeneous. We aimed at identifying pathways operative in the development of infratentorial ependymomas. EXPERIMENTAL DESIGN To do so, gene expression profiles of tumo...

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Human Cancer Biology The Transcription Factor Evi-1 Is Overexpressed, Promotes Proliferation, and Is Prognostically Unfavorable in Infratentorial Ependymomas

Purpose: Ependymomas are glial tumors of presumably radial glial origin that share morphologic similarities with ependymal cells. The molecular genetics of ependymomas of supratentorial, infratentorial, and spinal location is heterogeneous. We aimed at identifying pathways operative in the development of infratentorial ependymomas. Experimental Design: To do so, gene expression profiles of tumo...

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ژورنال

عنوان ژورنال: Neuro-Oncology

سال: 2010

ISSN: 1522-8517,1523-5866

DOI: 10.1093/neuonc/noq074